AUTOIMMUNE TEST
Autoimmune diseases are inherently difficult to diagnose due to their complex nature. Even the most experienced of practitioners may find them challenging. Some of the diseases such as Sjogren’s Syndrome, Mixed Connective Tissue Disease and Systemic Lupus Erythematosus often have overlapping symptoms while the patients cycle through periods of relapse and remission, further complicating the diagnosis process. Current testing methods lean heavily on interpreting results from panels that are typically limited at only three to five autoimmune disease markers. However, with such a narrowed range of markers tested, the patients may end up obtaining a delayed, incomplete or even incorrect diagnosis.
In order to accurately screen for diseases, the more information provided is helpful for an early and accurate diagnosis.
The Aurora Life Sciences autoimmune panel provides an extensive set of markers in one test. Our innovative and cost effective diagnostic tool, provides a expanded overview of an individual’s autoimmune status.
An affordable broad based screening test that indicates the presence or absence of autoimmune markers that are associated with common autoimmune diseases.
Click here to view a sample test results page from the AutoimmuneS
An expanded comprehensive report detailing the levels of each of the 30+ autoimmune markers tested.
Click here to view a sample test results page from the Autoimmune 30+
How are the tests used?
1. The prevalence of autoimmune disease is rising. The Autoimmune S is a low cost ($149) test for determining if one is negative for the autoimmune disease markers included in the panel. For those that test positive the next step is to order the comprehensive autoimmune 30+ test that provides the details of the autoimmune markers detected and associated disease(s). The cost is an additional $295 when ordering as follow up to the autoimmune S screen.
2. The Autoimmune 30+ ($395) identifies the activity levels of specific autoimmune markers present to monitor disease risk, disease activity or response to therapy.
Test results help guide the individual to what they can do to prevent or reverse progression of early markers to autoimmune disease. By providing results to your practitioner, one can become a partner in care as the therapies suggested for treatment are complementary to conventional medicine.
When To Get Tested?
Autoimmune disease markers develop over months to years and go through a long pre-clinical or pre-symptom stage before an autoimmune disease is diagnosed. It is during this early (pre-disease) stage that autoimmunity is most preventable, and reversible.
In the past, expensive diagnostic tests have not been used as a screening test for chronic disease of unknown cause and no known cure. Now that protocols are published for prevention and reversal of some chronic diseases (Coronary heart disease, diabetes, autoimmune disease) and low cost screening tests are available, screening and early detection are now being adopted by individuals and practitioners pursuing Therapeutic Lifestyle Change (TLC) 1,2,5,17,24,24 (ref Therapy page) for disease prevention, arrest and reversal.
If there are symptoms suggestive of an autoimmune disease it should be noted that autoantibodies are supportive of a diagnosis, however they may rarely occur without a disease or as a transient phenomenon during an infection. In some cases it may be appropriate to monitor the concentration of autoantibodies for the development, activity or prognosis of disease and the effect of treatment.
What are we testing for…
| Autoimmune Disease | Autoimmune Disease Marker |
|---|---|
| Sjogren's Syndrome (SS) | Ro60, La |
| Systemic Lupus Erythematosus (SLE) | Ro60, La Sm U1-snRNP A/C/68kD, dsDNA, Ku p70/p80, PCNA, ScL70(kDA), Ribosomal PO |
| Neonatal lupus (NL) | Ro60, Ro52 |
| Scleroderma | Ro60, U1-snRNP A/C/68kD, PMScl100(kDA),Sc70(kDA), La |
| Mixed Connective Tissue Disease (MCTD) | Ro60, U1-snRNP A/C/68kD, |
| Myositis | Ro52, U1-snRNP A/C/68kD |
| Primary Sjögren’s syndrome | La |
| Primary Biliary Cirrhosis | La, M2 |
| Pulmonary Hypertension | U1-snRNP A/C/68kD |
| Raynaud’s phenomenon | U1-snRNP A/C/68kD |
| Rheumatoid Arthritis (RA) | La, U1-snRNP A/C/68kD |
| Myositis | PMScl100(kDA) |
| Polymyositis | dsDNA, Ku p70/p80, Jo-1, U1-snRNP A/C/68kD |
| Dermatomyositis | Mi-2, Ku p70/p80, Jo-1, U1-snRNP A/C/68kD |
| Pulmonary Hypertension | Ku p70/p80 |
| Systemic sclerosis (SSc) | Ku, p70/p80, ScL70(kDA), CENP B |
| Crest Syndeome | CENP B |
| Primary biliary cirrhosis (PBC) | CENP B, M2, sp 100 |
| Polymyositis/Dermatomyositis | Jo-1 |
| Interstitial lung disease | Jo-1 |
| Central Nervous System (CNS) Diseaase | Ribosomal P0 |
| Autoimmune Hepatitis | La, LKM-1, LC-1, SLA |
| Celiac disease (CD) | tTG/IgA/IgG, DGP/IgA/IgG |
| Dermatitis Herpetiformis (DH) | tTG/IgA/IgG, DGP/IgA/IgG |
| Crohn’s disease (CD) | ASCA/IgA/IgG |
| Systemic Vasculitis | MPO, PR3 |
| necrotising glomerulonephritis | MPO |
| Cystic Fibrosis/Infection | BPI |
| Pernicious Anaemia | IFAB, AGPC |
| Atrophic Gastritis | IFAB |
| Chronic Thyroid disease | TPO |
| Hashimoto’s thyroiditis | TPO |
| Granulomatosis with Polyangiitis | PR3 |
| Autoimmune Atrophic Gastritis | AGPC |
| Congential Heart Block (CHB) | Ro 52 |
| Dermatomyositis | M2 |
| Autoimmune chronic active hepatitis type 2 | LC1 |
Autoantibody Markers Tested
Our test is a comprehensive set of autoantibody markers selected to provide an expanded overview of an individual’s autoimmune status.
- Bactericidal Permeability-Increasing Protein (BPI)
- Centromere Protein B (CENP-B)
- Deamidated Gliadin Peptide IgA and IgG (DGP)
- Double Stranded DNA (dsDNA)
- Gastric Parietal Cells (AGPC)
- IgA Status
- Intrinsic Factor (IFAB)
- Jo-1
- Ku
- La (SSB)
- Liver Cytosol (LC1)
- Liver/Kidney Microsomal (LKM-1)
- Mitochondria Type (M2)
- Myeloperoxidase (pANCA) (MPO)
- Nuclear Antigen (sp100)
- PM/Scl100 (PMScl100)
- Proliferating Cell Nuclear Antigen (PCNA)
- Proteinase 3 (PR3)
- Ribosomal P0
- Ro52 (SSA/TRIM21)
- Ro60 (SSA)
- Saccharomyces Cerevisiae IgA and IgG (ASCA)
- Scleroderma (SCL70)
- Smith (Sm)
- Soluble Liver Antigen (SLA)
- Thyroid Peroxidase (TPO)
- Tissue Transglutaminase IgA and IgG (tTG)
- Ribonucleoprotein (RNP)
- Glycoprotein GP210
- Glomerular Gasement Membrane (GBM)
- Signal Recognition Particle (SRP54)
- Chromatin Remodeling Enzyme (Mi-2)
Associated Autoimmune Diseases:
Tested autoantibody markers are associated with one or more of the following autoimmune diseases.
- Atrophic Gastritis
- Autoimmune Hepatitis
- Biliary Cirrhosis, Primary
- Celiac Disease
- CREST Syndrome
- Crohn’s Disease
- Dermatitis Herpetiformis
- Dermatomyositis
- Glomerular Basement Membrane Disease
- Goodpasture’s Syndrome
- Granulomatosis with Polyangiitis
- Lupus Erythematosus, Systemic
- Mixed Connective Tissue Disease
- Myositis
- Pernicious Anaemia
- Polymyositis
- Raynaud’s Phenomenon
- Scleroderma
- Sjögren’s Syndrome
- Systemic Sclerosis
- Thyroid Disease
Click here to view a sample test results page from the Autoimmune 30+.
How the Process Works
Upon receipt of an order, a sample collection kit will be sent to you. The test kit contains a sample collection vial, instructions for use and a pre-labeled, prepaid shipping pack. After receiving, take the sample kit to a blood draw location in your area.
Blood Draw Locations
Please note: Prior to a draw, verify that the draw center can process and pack the specimen per the instructions . A nominal service fee by the center may be charged.
– Any Lab Test Now is a national blood draw service with locations in many cities. They accept and process specialty test collection kits for a nominal service fee.
– Take the collection kit to your health care provider.
– Take the collection kit to your local hospital clinic.
– Contact your county health department as most offer phlebotomy services.
Within 2 weeks, we will email test results.
Consult a health care professional to review your results